Nanotechnology-COVID-19 Interface by Devasena T

Author:Devasena T.
Language: eng
Format: epub
ISBN: 9789813363007
Publisher: Springer Singapore

2′OMTase inhibitors

Dolutegravir and bictegravir

Interferes with mRNA capping and decreases its stability and subsequent translation machinery

II, III

NTPase inhibitors

Arylketoacids

Inhibits SARS CoV2 genome expression

II

Helicase inhibitors

Potassium bismuth citrate

Inhibits SARS CoV2 genome replication

II

RdRp inhibitors

Ribavirin

Aurin tricarboxylic acid (ATA)

Inhibits SARS CoV2 genome polymerization and replication

II

TMPRSS2 inhibitors

Camostat mesylate

Inhibits spike protein fusion to host cell

Suppresses the activity of cytokines interleukin-1beta (IL-1b) and interleukin-6 (IL-6) and controls inflammation

I, III, IV

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